ANAPC1

Across TCGA patient cohorts, ANAPC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,452 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANAPC1-associated proteins across cancer lineages are SNRPD3, MSH6, and POLR1E. Each is linked with ANAPC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ANAPC1-to-partner and partner-to-ANAPC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANAPC1 versus SNRPD3 in PDAC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC1→partner) and Y-score (partner→ANAPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SNRPD3 →	+0.334	+0.207	<.001	<.001	3	9
LSCC	MSH6 →	+0.649	+0.622	<.001	<.001	3	8
LUAD	POLR1E →	+0.298	+0.407	<.001	<.001	3	8
GBM	ADNP →	+0.403	+0.353	<.001	<.001	3	8
LSCC	UTP15 →	+0.351	+0.656	<.001	<.001	3	7
LSCC	UTP4 →	+0.385	+0.571	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,452 associations by consensus.

ANAPC1 vs SNRPD3 — PDAC

Explore this scatter interactively →