ANAPC1

Across TCGA patient cohorts, ANAPC1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,355 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANAPC1-associated genes across cancer lineages are TAF15, MYBL2, and TMEM97. Each is linked with ANAPC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANAPC1-to-partner and partner-to-ANAPC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANAPC1 versus TAF15 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC1→partner) and Y-score (partner→ANAPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TAF15 →	+0.620	+0.141	<.001	<.001	3	6
BRCA	MYBL2 →	+1.225	+0.124	.001	.006	3	5
LSCC	TMEM97 →	+1.183	+0.169	<.001	<.001	3	5
GBM	KIF18A →	+0.740	+0.115	<.001	<.001	3	5
GBM	CKAP2L →	+0.792	+0.146	<.001	<.001	3	5
LUAD	BUB1 →	+0.957	+0.153	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,355 associations by consensus.

ANAPC1 vs TAF15 — LSCC

Explore this scatter interactively →