ANAPC1

Across TCGA cell cohorts, ANAPC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,621 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ANAPC1-associated GO terms across cancer lineages are Metaphase/anaphase transition of cell cycle, Metaphase/anaphase transition of mitotic cell cycle, and Transcription initiation at RNA polymerase I promoter. Each is linked with ANAPC1 in more than 19 cancer types. Because this analysis shows association rather than direction, both ANAPC1-to-partner and partner-to-ANAPC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metaphase/anaphase transition of cell cycle grouped by ANAPC1-low versus ANAPC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC1→partner) and Y-score (partner→ANAPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Metaphase/anaphase transition of cell cycle →	+0.206	+0.945	<.001	<.001	3	20
BONE	Metaphase/anaphase transition of mitotic cell cycle →	+0.204	+0.922	<.001	<.001	3	20
BONE	Transcription initiation at RNA polymerase I promoter →	+0.154	+1.274	<.001	<.001	3	19
BLOOD_Myeloma	DNA replication initiation →	+0.182	+0.957	<.001	<.001	3	18
SOFT_TISSUE	Transcription by RNA polymerase I →	+0.118	+1.281	<.001	<.001	3	18
LIVER	rRNA 5'-end processing →	+0.174	+0.617	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,621 associations by consensus.

Metaphase/anaphase transition of cell cycle by ANAPC1 expression — BONE

Explore this box plot interactively →