AMZ2P3

Across TCGA patient cohorts, AMZ2P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,759 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AMZ2P3-associated GO terms across cancer lineages are Negative regulation of DNA metabolic process, Regulation of mitochondrial gene expression, and Obsolete histone methylation. Each is linked with AMZ2P3 in more than 5 cancer types. Because this analysis shows association rather than direction, both AMZ2P3-to-partner and partner-to-AMZ2P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA metabolic process grouped by AMZ2P3-low versus AMZ2P3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMZ2P3→partner) and Y-score (partner→AMZ2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of DNA metabolic process →	+0.126	+0.025	<.001	.004	3	6
STAD	Regulation of mitochondrial gene expression →	+0.151	+0.027	<.001	.003	3	4
STAD	Obsolete histone methylation →	+0.131	+0.024	<.001	.007	3	4
STAD	Regulation of chromatin organization →	+0.152	+0.049	<.001	.002	3	4
STAD	Negative regulation of TORC1 signaling →	+0.132	+0.024	<.001	.007	3	4
STAD	Negative regulation of telomere maintenance via telomere lengthening →	+0.133	+0.056	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,759 associations by consensus.

Negative regulation of DNA metabolic process by AMZ2P3 expression — STAD

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