Across TCGA patient cohorts, AMZ2P1 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AMZ2P1-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, PDCD4, and STAT3_pY705. Each is linked with AMZ2P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AMZ2P1-to-partner and partner-to-AMZ2P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMZ2P1→partner) and Y-score (partner→AMZ2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.714	+3.169	.010	.020	3	1
UCEC	PDCD4 →	-0.674	-3.169	.009	.020	3	1
UCEC	STAT3_pY705 →	-0.402	-3.169	.005	.020	3	1
UCEC	Bcl-2 →	-0.379	-3.143	.047	.020	3	1
UCEC	CD49b →	-0.334	-3.150	.032	.019	3	1
UCEC	Cyclin-B1 →	+0.796	+3.169	.009	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

AMZ2P1 survival (RNA) · tumor vs normal (RNA) · all AMZ2P1 data types