Across TCGA cell cohorts, AMZ2 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AMZ2-associated genes across cancer lineages are DAZ4, SLC13A1, and OR13C7. Each is linked with AMZ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AMZ2-to-partner and partner-to-AMZ2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMZ2→partner) and Y-score (partner→AMZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	DAZ4 →	+0.017	+3.977	<.001	.006	3	1
LIVER	SLC13A1 →	+0.012	+3.977	<.001	.006	3	1
LARGE_INTESTINE	OR13C7 →	+0.019	+4.415	<.001	.007	3	1
BLOOD_Leukemia	OR11H1 →	+0.080	+5.786	<.001	<.001	3	1
BLOOD_Leukemia	SLCO1C1 →	+0.096	+4.705	<.001	.003	3	1
BLOOD_Leukemia	CER1 →	+1.039	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

AMZ2 survival (RNA) · tumor vs normal (RNA) · all AMZ2 data types