Across TCGA cell cohorts, AMZ2 mutation is significantly associated with the mutation status of many other genes, with 338 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AMZ2-associated genes across cancer lineages are RABGAP1L, C1QC, and OC90. Each is linked with AMZ2 in more than 2 cancer types. Because this analysis shows association rather than direction, both AMZ2-to-partner and partner-to-AMZ2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMZ2→partner) and Y-score (partner→AMZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RABGAP1L →	+4.560	+4.309	.007	.007	1	3
SKIN	C1QC →	+4.824	+5.392	.004	.004	1	3
BLOOD_Leukemia	OC90 →	+4.560	+4.309	.007	.007	1	2
BLOOD_Leukemia	MUC22 →	+4.560	+4.309	.007	.007	1	2
SKIN	NRROS →	+4.239	+5.053	.007	.007	1	2
BLOOD_Leukemia	CACNA1I →	+2.823	+3.665	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 338 associations by consensus.

Exploration

AMZ2 survival (RNA) · tumor vs normal (RNA) · all AMZ2 data types