Across TCGA pan-cancer cohorts, AMYP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of AMYP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where AMYP1 RNA is repressed in tumor relative to normal tissue. In most cancer types AMYP1 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

KICH, KIRP, and KIRC are the cancer types where AMYP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AMYP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.047	.004	3	view →
KIRP	Male	All	−0.048	.042	2	view →
KIRC	All	All	−0.012	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: AMYP1 RNA expression & survival · all AMYP1 data types