Across TCGA pan-cancer cohorts, AMY1C Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated AMY1C data layer compared with 9 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher AMY1C Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated AMY1C expression acts as an unfavorable survival marker.

COAD are the cancer types where AMY1C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.111	0.871	<.001	24	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: AMY1C tumor-vs-normal RNA expression · all AMY1C data types