AMPH

Across TCGA patient cohorts, AMPH protein abundance is significantly associated with the RNA expression of many other genes, with 12,995 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AMPH-associated genes across cancer lineages are MEIS3, SHISAL1, and FBN1. Each is linked with AMPH in more than 6 cancer types. Because this analysis shows association rather than direction, both AMPH-to-partner and partner-to-AMPH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMPH versus MEIS3 in BRCA, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMPH→partner) and Y-score (partner→AMPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MEIS3 →	+1.568	+0.653	<.001	<.001	3	7
GBM	SHISAL1 →	+1.469	+0.854	<.001	<.001	3	7
BRCA	FBN1 →	+1.431	+0.731	<.001	<.001	3	7
BRCA	TCEAL7 →	+1.266	+0.855	<.001	<.001	3	7
UCEC	MEG8 →	+0.741	+0.561	<.001	<.001	3	7
BRCA	SRPX →	+1.330	+0.846	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,995 associations by consensus.

AMPH vs MEIS3 — BRCA

Explore this scatter interactively →