AMPH

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, AMPH RNA expression is significantly associated with the go_rna of many other GO terms, with 3,361 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AMPH-associated GO terms across cancer lineages are Golgi vesicle transport, Negative regulation of organelle assembly, and Protein localization to vacuole. Each is linked with AMPH in more than 8 cancer types. Because this analysis shows association rather than direction, both AMPH-to-partner and partner-to-AMPH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by AMPH-low versus AMPH-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMPH→partner) and Y-score (partner→AMPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINGolgi vesicle transport →+0.046+1.511<.001.00239
BLOOD_LeukemiaNegative regulation of organelle assembly →+0.062+0.245<.001.00139
BONEProtein localization to vacuole →+0.083+2.373.002.00238
BONEEndosomal transport →+0.063+2.496<.001<.00138
BLOOD_LeukemiaRegulation of heart rate by cardiac conduction →-0.067-0.131.003.00238
SKINPositive regulation of anaphase-promoting complex-dependent catabolic process →+0.091+1.693.001.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,361 associations by consensus.

Golgi vesicle transport by AMPH expression — SKIN

Box plot of Golgi vesicle transport in AMPH-low vs AMPH-high samples in SKIN.

Explore this box plot interactively →

Exploration