AMPD3

Across TCGA cell cohorts, AMPD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,167 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible AMPD3-associated GO terms across cancer lineages are IMP salvage, Regulation of intracellular transport, and Regulation of intracellular protein transport. Each is linked with AMPD3 in more than 16 cancer types. Because this analysis shows association rather than direction, both AMPD3-to-partner and partner-to-AMPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP salvage grouped by AMPD3-low versus AMPD3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMPD3→partner) and Y-score (partner→AMPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	IMP salvage →	-0.223	-1.228	<.001	<.001	3	17
BREAST	Regulation of intracellular transport →	+0.060	+0.848	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of intracellular protein transport →	+0.090	+1.111	<.001	<.001	3	14
URINARY_TRACT	Small GTPase-mediated signal transduction →	+0.060	+0.910	.006	.007	3	14
LIVER	Maintenance of protein location →	+0.127	+1.367	<.001	<.001	3	14
BONE	Viral process →	+0.087	+1.120	<.001	.006	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,167 associations by consensus.

IMP salvage by AMPD3 expression — OVARY

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