AMPD1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, AMPD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,051 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AMPD1-associated GO terms across cancer lineages are Ventricular cardiac muscle tissue morphogenesis, Muscle organ development, and Nerve development. Each is linked with AMPD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both AMPD1-to-partner and partner-to-AMPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ventricular cardiac muscle tissue morphogenesis grouped by AMPD1-low versus AMPD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMPD1→partner) and Y-score (partner→AMPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEVentricular cardiac muscle tissue morphogenesis →-0.177-0.879<.001.00135
BONEMuscle organ development →-0.158-0.951<.001.00335
LUNG_NSCLC_LUSCNerve development →-0.086-0.067<.001.00334
BONEPositive regulation of monoatomic ion transport →-0.115-0.773<.001<.00134
BONEStress response to metal ion →-0.217-0.757.001.00834
URINARY_TRACTDetection of external stimulus →-0.091-0.024.001.00534
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,051 associations by consensus.

Ventricular cardiac muscle tissue morphogenesis by AMPD1 expression — BONE

Box plot of Ventricular cardiac muscle tissue morphogenesis in AMPD1-low vs AMPD1-high samples in BONE.

Explore this box plot interactively →

Exploration