AMOTL1

Across TCGA patient cohorts, AMOTL1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,899 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible AMOTL1-associated genes across cancer lineages are CD93, ROBO4, and GYPC. Each is linked with AMOTL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both AMOTL1-to-partner and partner-to-AMOTL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMOTL1 versus CD93 in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMOTL1→partner) and Y-score (partner→AMOTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CD93 →	+1.205	+0.572	<.001	.001	3	6
CCRCC	ROBO4 →	+0.768	+0.321	<.001	<.001	3	6
COAD	GYPC →	+1.062	+0.486	.008	.006	3	6
HNSC	ST13P11 →	+0.537	+0.384	.003	.001	3	5
HNSC	CAV1 →	+1.176	+0.453	<.001	<.001	3	5
UCEC	CNRIP1 →	+0.775	+0.423	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,899 associations by consensus.

AMOTL1 vs CD93 — OV

Explore this scatter interactively →