Across TCGA pan-cancer cohorts, AMMECR1L mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated AMMECR1L data layer compared with 26 for mass-spec protein and 4 for mutation status.
The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher AMMECR1L mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated AMMECR1L expression acts as an unfavorable survival marker.
LSCC are the cancer types where AMMECR1L mass-spec protein most reproducibly stratifies survival.