AMMECR1L

Across TCGA cell cohorts, AMMECR1L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,176 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AMMECR1L-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Late viral transcription, and Heterochromatin organization. Each is linked with AMMECR1L in more than 15 cancer types. Because this analysis shows association rather than direction, both AMMECR1L-to-partner and partner-to-AMMECR1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by AMMECR1L-low versus AMMECR1L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMMECR1L→partner) and Y-score (partner→AMMECR1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of gene expression, epigenetic →	+0.085	+0.616	<.001	.001	3	16
BONE	Late viral transcription →	+0.172	+0.883	<.001	<.001	3	15
OVARY	Heterochromatin organization →	+0.080	+0.688	<.001	<.001	3	14
OESOPHAGUS	Cytosolic transport →	+0.059	+0.714	.002	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to organelle →	+0.061	+0.640	<.001	.003	3	13
LUNG_NSCLC_LUSC	Peptidyl-serine phosphorylation →	+0.092	+0.697	.001	.006	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,176 associations by consensus.

Negative regulation of gene expression, epigenetic by AMMECR1L expression — BONE

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