AMMECR1L

Across TCGA cell cohorts, AMMECR1L mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible AMMECR1L-associated genes across cancer lineages are DPRX and CST9. Each is linked with AMMECR1L in more than 1 cancer types. Because this analysis shows association rather than direction, both AMMECR1L-to-partner and partner-to-AMMECR1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DPRX grouped by AMMECR1L-low versus AMMECR1L-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMMECR1L→partner) and Y-score (partner→AMMECR1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DPRX →	+0.068	+5.321	<.001	.005	3	1
OVARY	CST9 →	+0.006	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

DPRX by AMMECR1L expression — CNS

Explore this box plot interactively →