AMMECR1

Across TCGA pan-cancer cohorts, AMMECR1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated AMMECR1 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher AMMECR1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated AMMECR1 expression acts as an unfavorable survival marker.

LSCC, HNSC, and LUAD are the cancer types where AMMECR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	II,III,IV	0.522	0.860	.037	5	view →
HNSC	DFS	Quartile	III,IV	0.552	0.845	.042	4	view →
LUAD	OS	Median	III,IV	0.276	0.673	.030	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

AMMECR1–LSCC (OS)

Open the LSCC breakdown →