AMMECR1

Across TCGA cell cohorts, AMMECR1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AMMECR1-associated genes across cancer lineages are CD300H, BPIFA1, and FAM25C. Each is linked with AMMECR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AMMECR1-to-partner and partner-to-AMMECR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by AMMECR1-low versus AMMECR1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMMECR1→partner) and Y-score (partner→AMMECR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1
BLOOD_Lymphoma	BPIFA1 →	+0.995	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	FAM25C →	+0.351	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD300H by AMMECR1 expression — LARGE_INTESTINE

Explore this box plot interactively →