AMFR

Across TCGA cell cohorts, AMFR RNA expression is significantly associated with the go_rna of many other GO terms, with 5,093 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AMFR-associated GO terms across cancer lineages are Regulation of Golgi inheritance, Regulation of hypoxia-induced intrinsic apoptotic signaling pathway, and Negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway. Each is linked with AMFR in more than 12 cancer types. Because this analysis shows association rather than direction, both AMFR-to-partner and partner-to-AMFR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Golgi inheritance grouped by AMFR-low versus AMFR-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMFR→partner) and Y-score (partner→AMFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.156	+0.854	.001	<.001	3	13
BONE	Regulation of hypoxia-induced intrinsic apoptotic signaling pathway →	+0.153	+1.469	<.001	.001	3	11
BONE	Negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway →	+0.153	+1.469	<.001	.001	3	11
BONE	Vacuole organization →	+0.064	+1.586	<.001	<.001	3	11
LARGE_INTESTINE	ERBB3 signaling pathway →	+0.182	+0.677	<.001	<.001	3	11
LARGE_INTESTINE	ERBB2-ERBB3 signaling pathway →	+0.182	+0.677	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,093 associations by consensus.

Regulation of Golgi inheritance by AMFR expression — UPPER_AERODIGESTIVE_TRACT

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