AMER3

Across TCGA patient cohorts, AMER3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,029 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AMER3-associated genes across cancer lineages are SLC16A8, SEPTIN3, and KIAA0930. Each is linked with AMER3 in more than 1 cancer types. Because this analysis shows association rather than direction, both AMER3-to-partner and partner-to-AMER3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMER3 versus SLC16A8 in GBM, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMER3→partner) and Y-score (partner→AMER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC16A8 →	+0.748	+0.475	.009	.003	3	1
GBM	SEPTIN3 →	+1.550	+0.456	.003	.005	3	1
GBM	KIAA0930 →	+0.551	+0.536	.002	<.001	3	1
GBM	CHADL →	+2.004	+0.657	.002	.002	3	1
GBM	SOS2 →	+0.504	+0.645	<.001	.002	3	1
GBM	DDHD1 →	+0.669	+0.820	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,029 associations by consensus.

AMER3 vs SLC16A8 — GBM

Explore this scatter interactively →