AMER3

Across TCGA patient cohorts, AMER3 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,256 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AMER3-associated proteins across cancer lineages are AARSD1, ACLY_T447, and ADAM9_S799. Each is linked with AMER3 in more than 1 cancer types. Because this analysis shows association rather than direction, both AMER3-to-partner and partner-to-AMER3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMER3 versus AARSD1 in GBM, with a Pearson correlation of 0.58.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AMER3→partner) and Y-score (partner→AMER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	AARSD1 →	+0.675	+0.799	<.001	<.001	3	1
GBM	ACLY_T447 →	-1.017	-0.592	<.001	<.001	3	1
GBM	ADAM9_S799 →	-0.857	-0.617	<.001	<.001	3	1
GBM	ADCY5_S666 →	+1.724	+0.781	.001	.001	3	1
GBM	ADD1_S12 →	+0.952	+0.540	<.001	.005	3	1
GBM	AFDN_S246 →	+0.772	+0.520	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,256 associations by consensus.

AMER3 vs AARSD1 — GBM

Explore this scatter interactively →