AMER3

Across TCGA cell cohorts, AMER3 RNA expression is significantly associated with the go_rna of many other GO terms, with 775 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible AMER3-associated GO terms across cancer lineages are Regulation of protein localization to nucleus, Positive regulation of protein localization to nucleus, and Negative regulation of glycogen metabolic process. Each is linked with AMER3 in more than 3 cancer types. Because this analysis shows association rather than direction, both AMER3-to-partner and partner-to-AMER3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to nucleus grouped by AMER3-low versus AMER3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMER3→partner) and Y-score (partner→AMER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of protein localization to nucleus →	+0.071	+1.529	<.001	.001	3	4
LUNG_SCLC	Positive regulation of protein localization to nucleus →	+0.089	+1.809	<.001	<.001	3	4
LUNG_SCLC	Negative regulation of glycogen metabolic process →	+0.135	+1.193	<.001	<.001	3	4
LUNG_SCLC	Mitotic cell cycle checkpoint signaling →	+0.064	+1.627	.001	.002	3	4
OESOPHAGUS	Endoplasmic reticulum to cytosol transport →	+0.150	+0.016	<.001	.007	3	3
OESOPHAGUS	Retrograde protein transport, ER to cytosol →	+0.150	+0.016	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 775 associations by consensus.

Regulation of protein localization to nucleus by AMER3 expression — LUNG_SCLC

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