AMER2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AMER2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,404 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AMER2-associated proteins across cancer lineages are PRKCB, GDI1, and HDGFL3. Each is linked with AMER2 in more than 2 cancer types. Because this analysis shows association rather than direction, both AMER2-to-partner and partner-to-AMER2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMER2 versus PRKCB in GBM, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AMER2→partner) and Y-score (partner→AMER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPRKCB →+0.447+1.123<.001<.00133
COADGDI1 →+0.324+0.019<.001.00133
GBMHDGFL3 →+0.539+1.518<.001<.00133
COADKCNMA1 →+0.665+0.025<.001<.00133
GBMOCIAD2 →-0.736-1.240.001<.00133
LUADFAM169A_S399 →+0.890+0.102<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,404 associations by consensus.

AMER2 vs PRKCB — GBM

Per-sample scatter of AMER2 vs PRKCB in GBM (Pearson r = 0.49).

Explore this scatter interactively →

Exploration