AMER2

Across TCGA cell cohorts, AMER2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,180 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AMER2-associated GO terms across cancer lineages are Glycosaminoglycan metabolic process, Endodermal cell differentiation, and Regulation of fibrinolysis. Each is linked with AMER2 in more than 4 cancer types. Because this analysis shows association rather than direction, both AMER2-to-partner and partner-to-AMER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycosaminoglycan metabolic process grouped by AMER2-low versus AMER2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMER2→partner) and Y-score (partner→AMER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Glycosaminoglycan metabolic process →	-0.095	-3.368	<.001	<.001	3	5
LUNG_SCLC	Endodermal cell differentiation →	-0.213	-1.942	<.001	<.001	3	5
BONE	Regulation of fibrinolysis →	-0.490	-4.021	<.001	<.001	3	5
BONE	Aminoglycan metabolic process →	-0.098	-3.175	<.001	<.001	3	5
BONE	Regulation of monoatomic ion transmembrane transport →	-0.079	-3.962	<.001	<.001	3	5
BONE	Negative regulation of retinoic acid receptor signaling pathway →	+0.158	+3.294	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,180 associations by consensus.

Glycosaminoglycan metabolic process by AMER2 expression — BONE

Explore this box plot interactively →