Across TCGA patient cohorts, AMER1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,289 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AMER1-associated proteins across cancer lineages are HCFC1, RAD21, and WDR5. Each is linked with AMER1 in more than 6 cancer types. Because this analysis shows association rather than direction, both AMER1-to-partner and partner-to-AMER1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AMER1→partner) and Y-score (partner→AMER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HCFC1 →	+0.262	+0.666	<.001	<.001	3	7
GBM	RAD21 →	+0.300	+0.386	<.001	<.001	3	7
GBM	WDR5 →	+0.288	+0.431	<.001	<.001	3	7
BRCA	ZNF462_S2172 →	+0.626	+0.624	<.001	<.001	3	6
LSCC	GTF3C4 →	+0.303	+0.501	<.001	<.001	3	6
GBM	HNRNPLL →	+0.274	+0.423	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,289 associations by consensus.

Exploration

AMER1 survival (RNA) · tumor vs normal (RNA) · all AMER1 data types