Across TCGA patient cohorts, AMER1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,194 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AMER1-associated genes across cancer lineages are SLC22A3, CERS6, and PROS1. Each is linked with AMER1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AMER1-to-partner and partner-to-AMER1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMER1→partner) and Y-score (partner→AMER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC22A3 →	+0.995	+0.378	.009	.001	3	2
BRCA	CERS6 →	-1.732	-1.275	.005	<.001	3	2
LSCC	PROS1 →	+0.724	+0.303	.003	.006	3	2
HNSC	RPL26P26 →	+1.114	+0.574	.001	.009	3	2
BRCA	OGFOD2 →	-0.301	-0.879	.001	<.001	3	2
BRCA	CHD6 →	-0.737	-0.778	.008	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,194 associations by consensus.

Exploration

AMER1 survival (RNA) · tumor vs normal (RNA) · all AMER1 data types