Across TCGA cell cohorts, AMER1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,444 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible AMER1-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase I promoter, Positive regulation of telomerase RNA localization to Cajal body, and Constitutive heterochromatin formation. Each is linked with AMER1 in more than 16 cancer types. Because this analysis shows association rather than direction, both AMER1-to-partner and partner-to-AMER1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMER1→partner) and Y-score (partner→AMER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Transcription initiation at RNA polymerase I promoter →	+0.179	+0.978	<.001	<.001	3	17
PANCREAS	Positive regulation of telomerase RNA localization to Cajal body →	+0.119	+1.054	<.001	<.001	3	15
LUNG_SCLC	Constitutive heterochromatin formation →	+0.118	+1.045	<.001	<.001	3	14
BONE	Epigenetic regulation of gene expression →	+0.099	+0.945	<.001	<.001	3	14
BONE	Nucleic acid transport →	+0.147	+0.930	<.001	<.001	3	14
BONE	RNA transport →	+0.147	+0.930	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,444 associations by consensus.

Exploration

AMER1 survival (RNA) · tumor vs normal (RNA) · all AMER1 data types