AMDHD2

Across TCGA patient cohorts, AMDHD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,159 significant associations in total. OV shows the largest number of these associations.

The most reproducible AMDHD2-associated GO terms across cancer lineages are Nucleotide-sugar biosynthetic process, UDP-N-acetylglucosamine biosynthetic process, and Secretion of lysosomal enzymes. Each is linked with AMDHD2 in more than 24 cancer types. Because this analysis shows association rather than direction, both AMDHD2-to-partner and partner-to-AMDHD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide-sugar biosynthetic process grouped by AMDHD2-low versus AMDHD2-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMDHD2→partner) and Y-score (partner→AMDHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Nucleotide-sugar biosynthetic process →	+0.051	+0.616	<.001	<.001	3	25
TGCT	UDP-N-acetylglucosamine biosynthetic process →	+0.066	+0.449	<.001	<.001	3	24
UCS	Secretion of lysosomal enzymes →	+0.059	+0.577	.001	.001	3	24
LAML	UDP-N-acetylglucosamine metabolic process →	+0.056	+0.684	<.001	<.001	3	23
TGCT	Regulation of ATP metabolic process →	+0.038	+0.488	<.001	.001	3	21
LAML	N-acetylneuraminate catabolic process →	+0.077	+0.679	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,159 associations by consensus.

Nucleotide-sugar biosynthetic process by AMDHD2 expression — LAML

Explore this box plot interactively →