AMDHD2

Across TCGA patient cohorts, AMDHD2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,032 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AMDHD2-associated genes across cancer lineages are AXL, KPNA2, and NHSL2. Each is linked with AMDHD2 in more than 6 cancer types. Because this analysis shows association rather than direction, both AMDHD2-to-partner and partner-to-AMDHD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMDHD2 versus AXL in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMDHD2→partner) and Y-score (partner→AMDHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AXL →	+0.918	+0.293	<.001	<.001	3	7
HNSC	KPNA2 →	-0.731	-0.246	.001	<.001	3	6
OV	NHSL2 →	+0.523	+0.177	.003	.009	3	6
BRCA	CYBRD1 →	+0.849	+0.182	.003	.007	3	6
UCEC	HNMT →	+0.671	+0.233	<.001	<.001	3	6
GBM	DAB2 →	+0.808	+0.263	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,032 associations by consensus.

AMDHD2 vs AXL — OV

Explore this scatter interactively →