AMDHD2

Across TCGA cell cohorts, AMDHD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,159 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible AMDHD2-associated GO terms across cancer lineages are N-acetylglucosamine catabolic process, Cellular detoxification of methylglyoxal, and Response to methylglyoxal. Each is linked with AMDHD2 in more than 18 cancer types. Because this analysis shows association rather than direction, both AMDHD2-to-partner and partner-to-AMDHD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N-acetylglucosamine catabolic process grouped by AMDHD2-low versus AMDHD2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMDHD2→partner) and Y-score (partner→AMDHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	N-acetylglucosamine catabolic process →	+0.162	+1.484	<.001	<.001	3	19
OESOPHAGUS	Cellular detoxification of methylglyoxal →	+0.161	+1.152	.005	.003	3	16
OESOPHAGUS	Response to methylglyoxal →	+0.161	+1.152	.005	.003	3	16
OESOPHAGUS	Cellular response to methylglyoxal →	+0.161	+1.152	.005	.003	3	16
BONE	Pre-mRNA catabolic process →	+0.168	+0.925	<.001	<.001	3	15
SKIN	Methylglyoxal metabolic process →	+0.141	+1.635	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,159 associations by consensus.

N-acetylglucosamine catabolic process by AMDHD2 expression — BONE

Explore this box plot interactively →