AMDHD1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, AMDHD1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. CNS shows the largest number of these associations.

The most reproducible AMDHD1-associated genes across cancer lineages are OR2J2. Each is linked with AMDHD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AMDHD1-to-partner and partner-to-AMDHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2J2 grouped by AMDHD1-low versus AMDHD1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMDHD1→partner) and Y-score (partner→AMDHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSOR2J2 →+0.026+4.981<.001.00831
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR2J2 by AMDHD1 expression — CNS

Box plot of OR2J2 in AMDHD1-low vs AMDHD1-high samples in CNS.

Explore this box plot interactively →

Exploration