Across TCGA pan-cancer cohorts, AMD1P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of AMD1P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where AMD1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types AMD1P1 is over-expressed in tumor, although a few such as BRCA and ESCA show the opposite, repressed pattern.

KIRC, BRCA, and ESCA are the cancer types where AMD1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AMD1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.142	<.001	8	view →
BRCA	Female	All	−0.112	.005	4	view →
ESCA	Female	All	−0.196	.010	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: AMD1P1 RNA expression & survival · all AMD1P1 data types