AMD1

Across TCGA pan-cancer cohorts, AMD1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated AMD1 data layer compared with 22 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher AMD1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated AMD1 expression acts as an unfavorable survival marker.

KIRP, STAD, and LUSC are the cancer types where AMD1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.574	0.903	.005	12	view →
STAD	OS	Median	All	0.097	0.667	<.001	6	view →
LUSC	DFS	Median	II,III,IV	0.199	0.748	.006	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LUAD	OS	Median	II,III,IV	0.250	0.709	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

AMD1–KIRP (OS)

Open the KIRP breakdown →