AMD1

Across TCGA cell cohorts, AMD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,619 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AMD1-associated GO terms across cancer lineages are Spermidine biosynthetic process, Spermine biosynthetic process, and Polyamine biosynthetic process. Each is linked with AMD1 in more than 19 cancer types. Because this analysis shows association rather than direction, both AMD1-to-partner and partner-to-AMD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spermidine biosynthetic process grouped by AMD1-low versus AMD1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMD1→partner) and Y-score (partner→AMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Spermidine biosynthetic process →	+0.241	+1.431	<.001	<.001	3	20
OESOPHAGUS	Spermine biosynthetic process →	+0.254	+1.431	<.001	<.001	3	19
URINARY_TRACT	Polyamine biosynthetic process →	+0.185	+0.841	.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.128	+0.934	<.001	<.001	3	17
SKIN	Ribosome localization →	+0.107	+0.932	<.001	<.001	3	16
SKIN	Ribosomal subunit export from nucleus →	+0.107	+0.932	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,619 associations by consensus.

Spermidine biosynthetic process by AMD1 expression — OESOPHAGUS

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