AMD1

Across TCGA cell cohorts, AMD1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible AMD1-associated genes across cancer lineages are SLC22A6. Each is linked with AMD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AMD1-to-partner and partner-to-AMD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC22A6 grouped by AMD1-low versus AMD1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMD1→partner) and Y-score (partner→AMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SLC22A6 →	+0.099	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SLC22A6 by AMD1 expression — LUNG_SCLC

Explore this box plot interactively →