AMBN

Across TCGA patient cohorts, AMBN RNA expression is significantly associated with the go_rna of many other GO terms, with 6,597 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AMBN-associated GO terms across cancer lineages are Regulation of organelle assembly, Regulation of actin filament bundle assembly, and Negative regulation of organelle assembly. Each is linked with AMBN in more than 9 cancer types. Because this analysis shows association rather than direction, both AMBN-to-partner and partner-to-AMBN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of organelle assembly grouped by AMBN-low versus AMBN-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMBN→partner) and Y-score (partner→AMBN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of organelle assembly →	+0.064	+0.211	<.001	.003	3	10
STAD	Regulation of actin filament bundle assembly →	+0.053	+0.076	<.001	<.001	3	10
ESCA	Negative regulation of organelle assembly →	+0.053	+0.196	<.001	.009	2	10
STAD	Regulation of cell division →	+0.046	+0.079	<.001	<.001	3	9
ESCA	Base-excision repair →	+0.069	+0.236	<.001	<.001	3	9
STAD	Nucleus organization →	+0.063	+0.109	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,597 associations by consensus.

Regulation of organelle assembly by AMBN expression — ESCA

Explore this box plot interactively →