AMBN

Across TCGA patient cohorts, AMBN protein abundance is significantly associated with the RNA expression of many other genes, with 239 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AMBN-associated genes across cancer lineages are UPB1, NFATC4, and MAGED2. Each is linked with AMBN in more than 1 cancer types. Because this analysis shows association rather than direction, both AMBN-to-partner and partner-to-AMBN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMBN versus UPB1 in LSCC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMBN→partner) and Y-score (partner→AMBN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UPB1 →	+0.161	+0.566	.006	.006	3	1
LSCC	NFATC4 →	-0.623	-0.891	.003	.002	3	1
LSCC	MAGED2 →	-0.405	-0.826	.004	.001	3	1
LSCC	HDAC5 →	-0.343	-0.726	.005	.004	3	1
LSCC	CDR2L →	-0.687	-0.748	.001	.008	3	1
LSCC	ST3GAL4 →	-0.449	-0.805	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 239 associations by consensus.

AMBN vs UPB1 — LSCC

Explore this scatter interactively →