AMBN

Across TCGA cell cohorts, AMBN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,242 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AMBN-associated GO terms across cancer lineages are Negative regulation of T-helper 1 type immune response, Regulation of double-strand break repair via homologous recombination, and Regulation of G0 to G1 transition. Each is linked with AMBN in more than 5 cancer types. Because this analysis shows association rather than direction, both AMBN-to-partner and partner-to-AMBN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of T-helper 1 type immune response grouped by AMBN-low versus AMBN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMBN→partner) and Y-score (partner→AMBN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of T-helper 1 type immune response →	-1.639	-1.144	<.001	<.001	3	6
BLOOD_Lymphoma	Regulation of double-strand break repair via homologous recombination →	+0.076	+0.162	<.001	.001	3	5
BLOOD_Lymphoma	Regulation of G0 to G1 transition →	+0.091	+0.131	<.001	.008	3	5
LUNG_NSCLC_LUSC	Dosage compensation by inactivation of X chromosome →	+0.076	+0.016	.006	.002	3	5
LUNG_SCLC	Oncostatin-M-mediated signaling pathway →	-0.194	-0.998	.009	.001	3	5
BONE	Bile acid signaling pathway →	+0.238	+0.974	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,242 associations by consensus.

Negative regulation of T-helper 1 type immune response by AMBN expression — BONE

Explore this box plot interactively →