ALYREF

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ALYREF mutation is significantly associated with the RNA expression of many other genes, with 657 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALYREF-associated genes across cancer lineages are RBMY1A3P, RAB9BP1, and RN7SL604P. Each is linked with ALYREF in more than 1 cancer types. Because this analysis shows association rather than direction, both ALYREF-to-partner and partner-to-ALYREF results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALYREF→partner) and Y-score (partner→ALYREF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SARCRBMY1A3P →+0.637+5.696<.001<.00132
HNSCRAB9BP1 →+0.075+5.822<.001.00332
SARCRN7SL604P →+0.231+4.498<.001.00532
SARCLINC02311 →+0.164+6.398<.001<.00132
BLCARNU2-71P →+0.253+3.910<.001.00332
BLCAMTATP6P13 →+0.055+3.735<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 657 associations by consensus.

Exploration