Across TCGA cell cohorts, ALYREF RNA expression is significantly associated with the RNA expression of many other genes, with 10,321 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ALYREF-associated genes across cancer lineages are CCDC137, SRSF2, and GPS1. Each is linked with ALYREF in more than 19 cancer types. Because this analysis shows association rather than direction, both ALYREF-to-partner and partner-to-ALYREF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALYREF→partner) and Y-score (partner→ALYREF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	CCDC137 →	+1.030	+1.030	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	SRSF2 →	+1.350	+1.420	<.001	.001	3	19
LUNG_NSCLC_LUSC	GPS1 →	+0.918	+0.897	.001	.003	2	20
BLOOD_Myeloma	MCM10 →	+1.946	+1.611	.001	.001	3	19
URINARY_TRACT	BIRC5 →	+1.307	+1.425	<.001	<.001	3	19
OESOPHAGUS	TUBA1B →	+1.411	+1.080	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,321 associations by consensus.

Exploration

ALYREF survival (RNA) · tumor vs normal (RNA) · all ALYREF data types