Across TCGA cell cohorts, ALYREF RNA expression is significantly associated with the go_rna of many other GO terms, with 4,594 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ALYREF-associated GO terms across cancer lineages are Cell cycle DNA replication, Mitotic DNA replication, and Regulation of DNA-templated DNA replication. Each is linked with ALYREF in more than 19 cancer types. Because this analysis shows association rather than direction, both ALYREF-to-partner and partner-to-ALYREF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALYREF→partner) and Y-score (partner→ALYREF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cell cycle DNA replication →	+0.159	+1.612	<.001	<.001	3	20
PANCREAS	Mitotic DNA replication →	+0.216	+1.137	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated DNA replication →	+0.141	+1.469	<.001	<.001	3	20
SOFT_TISSUE	Nuclear division →	+0.067	+0.975	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Nuclear DNA replication →	+0.157	+1.593	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.265	+1.815	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,594 associations by consensus.

Exploration

ALYREF survival (RNA) · tumor vs normal (RNA) · all ALYREF data types