ALPL

Across TCGA cell cohorts, ALPL RNA expression is significantly associated with the go_rna of many other GO terms, with 1,539 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ALPL-associated GO terms across cancer lineages are Cell division, Establishment of RNA localization, and Response to sodium phosphate. Each is linked with ALPL in more than 9 cancer types. Because this analysis shows association rather than direction, both ALPL-to-partner and partner-to-ALPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by ALPL-low versus ALPL-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALPL→partner) and Y-score (partner→ALPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cell division →	+0.058	+1.293	.007	.005	3	9
PANCREAS	Establishment of RNA localization →	+0.067	+0.276	.002	.005	2	10
LUNG_SCLC	Response to sodium phosphate →	-0.287	-2.053	<.001	<.001	3	8
PANCREAS	RNA localization →	+0.073	+0.378	.001	.001	2	9
SKIN	Regulation of protein localization to Cajal body →	+0.051	+0.540	.005	.009	3	7
SKIN	Positive regulation of protein localization to Cajal body →	+0.051	+0.540	.005	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,539 associations by consensus.

Cell division by ALPL expression — BREAST

Explore this box plot interactively →