Across TCGA patient cohorts, ALPK2 protein abundance is significantly associated with the RNA expression of many other genes, with 903 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ALPK2-associated genes across cancer lineages are GFPT2, CCL23, and CD209. Each is linked with ALPK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALPK2-to-partner and partner-to-ALPK2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALPK2→partner) and Y-score (partner→ALPK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	GFPT2 →	-1.732	-1.992	.009	.008	3	2
PDAC	CCL23 →	-1.236	-1.623	.001	.008	3	2
PDAC	CD209 →	-0.870	-2.096	<.001	<.001	3	2
CCRCC	CRYBB1 →	-0.449	-0.479	<.001	<.001	3	1
CCRCC	TTC28 →	+0.395	+0.384	.005	.001	3	1
CCRCC	RSPH14 →	+0.570	+0.430	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 903 associations by consensus.

Exploration

ALPK2 survival (RNA) · tumor vs normal (RNA) · all ALPK2 data types