Across TCGA cell cohorts, ALPK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,124 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ALPK2-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Positive regulation of cell-substrate junction organization, and Peptidyl-lysine oxidation. Each is linked with ALPK2 in more than 13 cancer types. Because this analysis shows association rather than direction, both ALPK2-to-partner and partner-to-ALPK2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALPK2→partner) and Y-score (partner→ALPK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.209	+2.875	<.001	<.001	3	14
BONE	Positive regulation of cell-substrate junction organization →	+0.181	+2.902	<.001	<.001	3	13
URINARY_TRACT	Peptidyl-lysine oxidation →	+1.585	+2.176	<.001	.005	3	12
BONE	Positive regulation of actin filament bundle assembly →	+0.201	+2.865	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Negative regulation of Rho protein signal transduction →	+0.206	+4.077	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Golgi to plasma membrane protein transport →	+0.158	+4.622	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,124 associations by consensus.

Exploration

ALPK2 survival (RNA) · tumor vs normal (RNA) · all ALPK2 data types