ALOXE3P1

Across TCGA pan-cancer cohorts, ALOXE3P1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ALOXE3P1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher ALOXE3P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ALOXE3P1 expression acts as an unfavorable survival marker, although some lineages such as OV and BRCA show a favorable association.

KICH, LIHC, and CHOL are the cancer types where ALOXE3P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.690	0.982	<.001	66	view →
LIHC	OS	Quartile	II,III,IV	0.402	0.664	<.001	60	view →
CHOL	DFS	Median	II,III,IV	0.084	0.575	<.001	52	view →
OV	DFS	Tertile	All	0.215	0.128	.004	34	view →
BRCA	DFS	Median	IV	0.717	0.315	.003	18	view →
THCA	DFS	Tertile	III,IV	0.826	0.918	.020	14	view →
LGG	DFS	Tertile	All	0.859	0.763	.006	14	view →
PRAD	DFS	Quartile	All	0.830	0.945	.001	12	view →
HNSC	OS	Quartile	II,III,IV	0.539	0.277	.013	11	view →
ACC	DFS	Quartile	All	0.286	0.646	.010	10	view →
DLBC	DFS	Quartile	III,IV	0.070	0.833	.014	9	view →
READ	DFS	Tertile	IV	0.179	0.936	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ALOXE3P1–KICH (OS)

Open the KICH breakdown →