ALOXE3

Across TCGA cell cohorts, ALOXE3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,315 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ALOXE3-associated GO terms across cancer lineages are Maintenance of cell polarity, Sperm mitochondrial sheath assembly, and Lipoxygenase pathway. Each is linked with ALOXE3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ALOXE3-to-partner and partner-to-ALOXE3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of cell polarity grouped by ALOXE3-low versus ALOXE3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOXE3→partner) and Y-score (partner→ALOXE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Maintenance of cell polarity →	+0.106	+0.631	.006	.006	3	8
LARGE_INTESTINE	Sperm mitochondrial sheath assembly →	-0.164	-0.704	.004	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Lipoxygenase pathway →	-0.232	-1.340	.003	<.001	2	8
BREAST	Peroxisome proliferator activated receptor signaling pathway →	-0.079	-0.569	<.001	<.001	3	7
STOMACH	Response to gamma radiation →	+0.090	+0.587	<.001	.009	3	6
BLOOD_Lymphoma	Positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential →	+1.165	+0.131	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,315 associations by consensus.

Maintenance of cell polarity by ALOXE3 expression — OESOPHAGUS

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