ALOX5AP

Across TCGA patient cohorts, ALOX5AP protein abundance is significantly associated with the protein abundance of many other proteins, with 26,750 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALOX5AP-associated proteins across cancer lineages are FCER1G_T78, MYO1F, and ALOX5. Each is linked with ALOX5AP in more than 9 cancer types. Because this analysis shows association rather than direction, both ALOX5AP-to-partner and partner-to-ALOX5AP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALOX5AP versus FCER1G_T78 in OV, with a Pearson correlation of 0.60.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX5AP→partner) and Y-score (partner→ALOX5AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FCER1G_T78 →	+2.331	+0.709	<.001	.001	3	10
GBM	MYO1F →	+0.591	+0.694	<.001	<.001	3	10
GBM	ALOX5 →	+0.715	+0.741	<.001	<.001	3	9
LSCC	SPN_S355 →	+0.954	+0.758	<.001	<.001	3	9
OV	TNFAIP8L2 →	+0.703	+0.898	.001	.002	3	9
UCEC	TYROBP →	+0.841	+0.991	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,750 associations by consensus.

ALOX5AP vs FCER1G_T78 — OV

Explore this scatter interactively →