Across TCGA pan-cancer cohorts, ALOX15P2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ALOX15P2’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ALOX15P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ALOX15P2 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

LUAD, KICH, and KIRC are the cancer types where ALOX15P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ALOX15P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.521	<.001	4	view →
KICH	All	All	−0.155	.012	4	view →
KIRC	Male	All	−0.051	.004	4	view →
PAAD	All	All	−0.042	.033	2	view →
KIRP	All	II,III,IV	+0.014	.028	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: ALOX15P2 RNA expression & survival · all ALOX15P2 data types