ALOX15B

Across TCGA patient cohorts, ALOX15B protein abundance is significantly associated with the RNA expression of many other genes, with 10,266 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALOX15B-associated genes across cancer lineages are KPNB1, HELLS, and C5AR2. Each is linked with ALOX15B in more than 3 cancer types. Because this analysis shows association rather than direction, both ALOX15B-to-partner and partner-to-ALOX15B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALOX15B versus KPNB1 in LSCC, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX15B→partner) and Y-score (partner→ALOX15B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KPNB1 →	-0.397	-0.335	<.001	<.001	3	4
LSCC	HELLS →	-1.068	-0.565	<.001	<.001	3	4
GBM	C5AR2 →	+0.543	+0.563	.002	.001	3	4
LSCC	SPC25 →	-0.757	-0.397	<.001	<.001	3	4
LSCC	E2F7 →	-0.848	-0.429	<.001	<.001	3	4
HNSC	BUD23 →	-0.497	-0.546	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,266 associations by consensus.

ALOX15B vs KPNB1 — LSCC

Explore this scatter interactively →